[Abdominal Aortic Aneurysm:Pathological Mechanism and Animal Model].

Fu, Hui; Zhou, Can-Can; Li, Dong-Jie; Shen, Fu-Ming

Fu, Hui; Zhou, Can-Can; Li, Dong-Jie; Shen, Fu-Ming.

Afiliação

Fu H; Department of Pharmacy,Shanghai Tenth People's Hospital,Tongji University School of Medicine,Tongji University,Shanghai 200072,China.
Zhou CC; Department of Pharmacy,Shanghai Tenth People's Hospital,Tongji University School of Medicine,Tongji University,Shanghai 200072,China.
Li DJ; Department of Pharmacy,Shanghai Tenth People's Hospital,Tongji University School of Medicine,Tongji University,Shanghai 200072,China.
Shen FM; Department of Pharmacy,Shanghai Tenth People's Hospital,Tongji University School of Medicine,Tongji University,Shanghai 200072,China.

Zhongguo Yi Xue Ke Xue Yuan Xue Bao ; 44(3): 516-520, 2022 Jun.

Article em Zh | MEDLINE | ID: mdl-35791953

ABSTRACT

ABSTRACT

Abdominal aortic aneurysm is defined as a dilated aorta with a diameter at least 1.5 times of the normal aorta.There is no effective drug for AAA.We summarized the high-risk factors,pathologic features,current therapies,and animal models in the pre-clinical study to gain comprehensive understanding of AAA.With this review,we aim to provide scientific support for the mining of therapeutic targets for AAA.

Assuntos

Aneurisma da Aorta Abdominal; Animais; Aorta; Modelos Animais de Doenças; Fatores de Risco

Palavras-chave

abdominal aortic aneurysm; animal models; high-risk factors; pathologic features; therapies

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aneurisma da Aorta Abdominal Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: Zh Revista: Zhongguo Yi Xue Ke Xue Yuan Xue Bao Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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