Your browser doesn't support javascript.
loading
[Validation of a DSM-5-based screening test using digital phenotyping in the Russian population]. / Validatsiya skriningovogo testa, osnovannogo na kriteriyakh DSM-5, metodom tsifrovogo fenotipirovaniya na rossiiskoi populyatsii.
Kasyanov, E D; Verbitskaya, E V; Rakitko, A S; Ilyinsky, V V; Rukavishnikov, G V; Neznanov, N G; Kibitov, A O; Mazo, G E.
Afiliação
  • Kasyanov ED; Bekhterev National Medical Research Center for Psychiatry and Neurology, St. Petersburg, Russia.
  • Verbitskaya EV; Pavlov First St. Petersburg Medical University, St. Petersburg, Russia.
  • Rakitko AS; Genotek LLC, Moscow, Russia.
  • Ilyinsky VV; Genotek LLC, Moscow, Russia.
  • Rukavishnikov GV; Bekhterev National Medical Research Center for Psychiatry and Neurology, St. Petersburg, Russia.
  • Neznanov NG; Bekhterev National Medical Research Center for Psychiatry and Neurology, St. Petersburg, Russia.
  • Kibitov AO; Pavlov First St. Petersburg Medical University, St. Petersburg, Russia.
  • Mazo GE; Bekhterev National Medical Research Center for Psychiatry and Neurology, St. Petersburg, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova ; 122(6. Vyp. 2): 64-70, 2022.
Article em Ru | MEDLINE | ID: mdl-35797198
OBJECTIVE: To evaluate the validity of a depression and anxiety screening test based on DSM-5 diagnostic criteria to identify cases of these conditions simultaneously assessed with the validated Hospital Anxiety and Depression Scale (HADS) in a population sample by digital phenotyping. MATERIAL AND METHODS: This cross-validation study included 5.116 respondents (mean age 36.9 (9.8)), of which 49.4% (2526) were women. The depression and anxiety screening test was done in electronic form and based on the DSM-5 diagnostic criteria for major depressive disorder and generalized anxiety disorder. The validated HADS scale was used as a standard test. The categories of depression (HADS-D) and anxiety (HADS-A) phenotypes were formed with a cutoff of ≥8 points and ≥11 points. The main parameters of the validity of the screening test were calculated, including accuracy (Ac), sensitivity (Sn) and specificity (Sp) with their 95% confidence intervals [CI]. RESULTS: The prevalence of current depression and anxiety according to the screening test was 7.8% (400) and 12.5% (639), respectively. The prevalence of lifetime depression was 25.9% (1327). For the HADS-D depression subscale with cut-offs of ≥11 and ≥8 points, the prevalence of depression was 3.4% (174) and 15% (766), respectively. For the HADS-A anxiety subscale with cut-offs of ≥11 and ≥8 points, the prevalence of anxiety was 8.9% (456) and 31.8% (1628), respectively. For HADS-D and HADS-A with a cutoff of ≥11 points, the parameters of current depression were Ac=92%, Sn=47% (CI 95% [39-54]), Sp=94% (CI 95% [93-94]), lifetime depression - Ac=75%, Sn=63% (CI 95% [56-70]), Sp=75% (CI 95% [74-77]) and current anxiety - Ac=88%, Sn=54% (CI 95% [50-59]) and Sp=92% (CI 95% [90-92]). For HADS-D and HADS-A with a cutoff of ≥8 points, the parameters of current depression were Ac=86%, Sn=30% (CI 95% [27-33]), Sp=96% (CI 95% [95-97]), lifetime depression - Ac=74%, Sn=51% (CI 95% [48-55]), Sp=75% 79% (CI 95% [77-80]) and current anxiety - Ac=75%, Sn=31% (CI 95% [29-33]), Sp=96% (95% CI [95-97]). CONCLUSION: The high Ac and Sp of this test allows it to be used for screening purposes to identify (but not exclude) cases of depression and anxiety in the population. However, further studies are needed to validate the screening test using a diagnostic interview with a physician.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Depressivo Maior Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Female / Humans / Male Idioma: Ru Revista: Zh Nevrol Psikhiatr Im S S Korsakova Assunto da revista: NEUROLOGIA / PSIQUIATRIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Federação Russa País de publicação: Federação Russa

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Depressivo Maior Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Female / Humans / Male Idioma: Ru Revista: Zh Nevrol Psikhiatr Im S S Korsakova Assunto da revista: NEUROLOGIA / PSIQUIATRIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Federação Russa País de publicação: Federação Russa