Prediction and verification of potential lead analgesic and antiarrhythmic components in Corydalis yanhusuo W. T. Wang based on voltage-gated sodium channel proteins.

Sun, Jianfang; Liu, Xin; Zhao, Shangfeng; Zhang, Suli; Yang, Liying; Zhang, Jinghai; Zhao, Mingyi; Xu, Yijia

Sun, Jianfang; Liu, Xin; Zhao, Shangfeng; Zhang, Suli; Yang, Liying; Zhang, Jinghai; Zhao, Mingyi; Xu, Yijia.

Afiliação

Sun J; School of Life Sciences and Biopharmaceutical Science, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, China.
Liu X; School of Life Sciences and Biopharmaceutical Science, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, China.
Zhao S; School of Life Sciences and Biopharmaceutical Science, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, China.
Zhang S; School of Life Sciences and Biopharmaceutical Science, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, China.
Yang L; School of Life Sciences and Biopharmaceutical Science, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, China.
Zhang J; School of Medical Devices, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, China.
Zhao M; School of Life Sciences and Biopharmaceutical Science, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, China. Electronic address: zhaomingyi@syphu.edu.cn.
Xu Y; School of Life Sciences and Biopharmaceutical Science, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, China. Electronic address: xuyijia@syphu.edu.cn.

Int J Biol Macromol ; 216: 537-546, 2022 Sep 01.

Article em En | MEDLINE | ID: mdl-35809671

Assuntos

Corydalis; Medicamentos de Ervas Chinesas; Canais de Sódio Disparados por Voltagem; Analgésicos/farmacologia; Analgésicos/uso terapêutico; Antiarrítmicos; Corydalis/química; Medicamentos de Ervas Chinesas/química; Medicamentos de Ervas Chinesas/farmacologia; Simulação de Acoplamento Molecular; Dor; Extratos Vegetais/química

Palavras-chave

Arrhythmia; Corydalis yanhusuo; Nav1.5; Nav1.7; Pain; VGSCs

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Corydalis / Canais de Sódio Disparados por Voltagem Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Int J Biol Macromol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China País de publicação: Holanda

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