Microwave synthesis and antimalarial screening of novel 4-amino benzoic acid (PABA)-substituted pyrimidine derivatives as <i>Plasmodium falciparum</i> dihydrofolate reductase inhibitors.

Choudhury, Ayesha Aktar Khanam; Vinayagam, Sathishkumar; Adhikari, Nayana; Ghosh, Surajit Kumar; Sattu, Kamaraj

Microwave synthesis and antimalarial screening of novel 4-amino benzoic acid (PABA)-substituted pyrimidine derivatives as Plasmodium falciparum dihydrofolate reductase inhibitors.

Choudhury, Ayesha Aktar Khanam; Vinayagam, Sathishkumar; Adhikari, Nayana; Ghosh, Surajit Kumar; Sattu, Kamaraj.

Afiliação

Choudhury AAK; Department of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, 786004 Assam India.
Vinayagam S; Department of Biotechnology, PG Extension Centre, Periyar University, Dharmapuri, 636701 Tamil Nadu India.
Adhikari N; Department of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, 786004 Assam India.
Ghosh SK; Department of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, 786004 Assam India.
Sattu K; Department of Biotechnology, PG Extension Centre, Periyar University, Dharmapuri, 636701 Tamil Nadu India.

3 Biotech ; 12(8): 170, 2022 Aug.

Article em En | MEDLINE | ID: mdl-35845109

Palavras-chave

Antimalarial activity; Microwave organic synthesis; Pf-DHFR; Plasmodium falciparum; Pyrimidine; p-Aminobenzoic acid

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Screening_studies Idioma: En Revista: 3 Biotech Ano de publicação: 2022 Tipo de documento: Article País de publicação: Alemanha

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