Your browser doesn't support javascript.
loading
Clinical impact of central nervous system-directed therapies on intravascular large B-cell lymphoma: A single institution's experience.
Takahashi, Hiromichi; Nishimaki, Haruna; Nakanishi, Yoko; Hamada, Takashi; Nakagawa, Masaru; Iizuka, Kazuhide; Uchino, Yoshihito; Iriyama, Noriyoshi; Miura, Katsuhiro; Nakayama, Tomohiro; Masuda, Shinobu; Hatta, Yoshihiro; Nakamura, Hideki.
Afiliação
  • Takahashi H; Department of Medicine Division of Hematology and Rheumatology Nihon University School of Medicine Tokyo Japan.
  • Nishimaki H; Department of Pathology and Microbiology Division of Laboratory Medicine Nihon University School of Medicine Tokyo Japan.
  • Nakanishi Y; Department of Pathology and Microbiology Division of Oncologic Pathology Nihon University School of Medicine Tokyo Japan.
  • Hamada T; Department of Pathology and Microbiology Division of Oncologic Pathology Nihon University School of Medicine Tokyo Japan.
  • Nakagawa M; Department of Medicine Division of Hematology and Rheumatology Nihon University School of Medicine Tokyo Japan.
  • Iizuka K; Department of Medicine Division of Hematology and Rheumatology Nihon University School of Medicine Tokyo Japan.
  • Uchino Y; Department of Medicine Division of Hematology and Rheumatology Nihon University School of Medicine Tokyo Japan.
  • Iriyama N; Department of Pathology and Microbiology Division of Laboratory Medicine Nihon University School of Medicine Tokyo Japan.
  • Miura K; Department of Medicine Division of Hematology and Rheumatology Nihon University School of Medicine Tokyo Japan.
  • Nakayama T; Department of Medicine Division of Hematology and Rheumatology Nihon University School of Medicine Tokyo Japan.
  • Masuda S; Department of Medicine Division of Hematology and Rheumatology Nihon University School of Medicine Tokyo Japan.
  • Hatta Y; Department of Pathology and Microbiology Division of Laboratory Medicine Nihon University School of Medicine Tokyo Japan.
  • Nakamura H; Department of Pathology and Microbiology Division of Oncologic Pathology Nihon University School of Medicine Tokyo Japan.
EJHaem ; 3(2): 467-470, 2022 May.
Article em En | MEDLINE | ID: mdl-35846032
ABSTRACT
Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of B-cell lymphoma characterized by aggressive disease progression with a high incidence of central nervous system (CNS) involvement. We retrospectively analyzed 16 patients with de novo IVLBCL treated at our hospital between 2004 and 2018 with either standard therapy plus CNS-directed therapy or standard therapy alone. CNS-directed therapy was associated with a significantly better 2-year CNS-free survival (100% vs. 63%, p = 0.0191), despite no significant effects on progression-free or overall survival. Further studies should assess CNS-focused treatment in patients with IVLBCL with or without primary CNS involvement.
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: EJHaem Ano de publicação: 2022 Tipo de documento: Article País de publicação: EEUU / ESTADOS UNIDOS / ESTADOS UNIDOS DA AMERICA / EUA / UNITED STATES / UNITED STATES OF AMERICA / US / USA
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: EJHaem Ano de publicação: 2022 Tipo de documento: Article País de publicação: EEUU / ESTADOS UNIDOS / ESTADOS UNIDOS DA AMERICA / EUA / UNITED STATES / UNITED STATES OF AMERICA / US / USA