Revisiting the concept of childhood preleukemia.
Trends Cancer
; 8(11): 887-889, 2022 11.
Article
em En
| MEDLINE
| ID: mdl-35871053
ABSTRACT
Preleukemic has been used to describe children with a propensity to develop B cell acute lymphoblastic leukemia (B-ALL). However, leukemia-predisposing mutations can also be present in differentiated cells unable to transform. We postulate that preleukemia should only be used when such mutations arise in progenitors capable of evolving to B-ALL.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pré-Leucemia
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
Limite:
Child
/
Humans
Idioma:
En
Revista:
Trends Cancer
Ano de publicação:
2022
Tipo de documento:
Article