The impact of sepsis on hepatic drug metabolism in critically ill patients: a narrative review.

Ewoldt, Tim Mj; Abdulla, Alan; Hunfeld, Nicole; Li, Letao; Smeets, Tim J L; Gommers, Diederik; Koch, Birgit C P; Endeman, Henrik

Ewoldt, Tim Mj; Abdulla, Alan; Hunfeld, Nicole; Li, Letao; Smeets, Tim J L; Gommers, Diederik; Koch, Birgit C P; Endeman, Henrik.

Afiliação

Ewoldt TM; Department of Intensive Care, Erasmus University Medical Center, Rotterdam, The Netherlands.
Abdulla A; Department of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands.
Hunfeld N; Department of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands.
Li L; Department of Intensive Care, Erasmus University Medical Center, Rotterdam, The Netherlands.
Smeets TJL; Department of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands.
Gommers D; Department of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands.
Koch BCP; Department of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands.
Endeman H; Department of Intensive Care, Erasmus University Medical Center, Rotterdam, The Netherlands.

Expert Opin Drug Metab Toxicol ; 18(6): 413-421, 2022 Jun.

Article em En | MEDLINE | ID: mdl-35912845

Assuntos

Estado Terminal; Sepse; Humanos; Fígado/metabolismo; Sepse/tratamento farmacológico

Palavras-chave

Drug metabolism; hepatic metabolism; pharmacokinetics; sepsis; septic shock

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estado Terminal / Sepse Tipo de estudo: Systematic_reviews Limite: Humans Idioma: En Revista: Expert Opin Drug Metab Toxicol Assunto da revista: METABOLISMO / TOXICOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda País de publicação: Reino Unido

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