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Targeting acetyl-CoA metabolism attenuates the formation of fear memories through reduced activity-dependent histone acetylation.
Alexander, Desi C; Corman, Tanya; Mendoza, Mariel; Glass, Andrew; Belity, Tal; Wu, Ranran; Campbell, Rianne R; Han, Joseph; Keiser, Ashley A; Winkler, Jeffrey; Wood, Marcelo A; Kim, Thomas; Garcia, Benjamin A; Cohen, Hagit; Mews, Philipp; Egervari, Gabor; Berger, Shelley L.
Afiliação
  • Alexander DC; Epigenetics Institute, University of Pennsylvania, Philadelphia, PA 19104.
  • Corman T; Department of Genetics, University of Pennsylvania, Philadelphia, PA 19104.
  • Mendoza M; Epigenetics Institute, University of Pennsylvania, Philadelphia, PA 19104.
  • Glass A; Epigenetics Institute, University of Pennsylvania, Philadelphia, PA 19104.
  • Belity T; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Wu R; Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104.
  • Campbell RR; Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva, 8410501, Israel.
  • Han J; Epigenetics Institute, University of Pennsylvania, Philadelphia, PA 19104.
  • Keiser AA; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Winkler J; Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697.
  • Wood MA; Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697.
  • Kim T; Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697.
  • Garcia BA; Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104.
  • Cohen H; Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697.
  • Mews P; Epivario, Inc., Philadelphia, PA 19104.
  • Egervari G; Epigenetics Institute, University of Pennsylvania, Philadelphia, PA 19104.
  • Berger SL; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Proc Natl Acad Sci U S A ; 119(32): e2114758119, 2022 08 09.
Article em En | MEDLINE | ID: mdl-35921439
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetilcoenzima A / Acetato-CoA Ligase / Histonas / Condicionamento Clássico / Medo / Consolidação da Memória Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetilcoenzima A / Acetato-CoA Ligase / Histonas / Condicionamento Clássico / Medo / Consolidação da Memória Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article País de publicação: Estados Unidos