Cytotoxic effects of extracts obtained from plants of the Oleaceae family: bio-guided isolation and molecular docking of new secoiridoids from <i>Jasminum humile</i>.

Mansour, Khaled Ahmed; Elbermawi, Ahmed; Al-Karmalawy, Ahmed A; Lahloub, Mohamed-Farid; El-Neketi, Mona

Cytotoxic effects of extracts obtained from plants of the Oleaceae family: bio-guided isolation and molecular docking of new secoiridoids from Jasminum humile.

Mansour, Khaled Ahmed; Elbermawi, Ahmed; Al-Karmalawy, Ahmed A; Lahloub, Mohamed-Farid; El-Neketi, Mona.

Afiliação

Mansour KA; Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Elbermawi A; Department of Pharmacognosy, Faculty of Pharmacy, Horus University in Egypt, New Damietta, Egypt.
Al-Karmalawy AA; Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Lahloub MF; Department of Pharmaceutical Medicinal Chemistry, Faculty of Pharmacy, Horus University in Egypt, New Damietta, Egypt.
El-Neketi M; Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.

Pharm Biol ; 60(1): 1374-1383, 2022 Dec.

Article em En | MEDLINE | ID: mdl-35961303

Assuntos

Antineoplásicos; Jasminum; Oleaceae; Antineoplásicos/farmacologia; Doxorrubicina; Humanos; Iridoides; Jasminum/química; Simulação de Acoplamento Molecular; Extratos Vegetais/química; Extratos Vegetais/farmacologia

Palavras-chave

MTT assay; SAR; Structure elucidation; anticancer; biological activity; selectivity index

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oleaceae / Jasminum / Antineoplásicos Limite: Humans Idioma: En Revista: Pharm Biol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Egito País de publicação: Reino Unido

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