Receptor-ligand affinity-based screening and isolation of water-soluble 5-lipoxygenase inhibitors from Phellinus igniarius.

Liu, Ruoyao; Zhang, Yuchi; Li, Sainan; Liu, Chunming; Zhuang, Siyuan; Zhou, Xu; Li, Yanjie; Liang, Jiaqi

Liu, Ruoyao; Zhang, Yuchi; Li, Sainan; Liu, Chunming; Zhuang, Siyuan; Zhou, Xu; Li, Yanjie; Liang, Jiaqi.

Afiliação

Liu R; Central Laboratory, Changchun Normal University, No. 677 North Changji Road, Erdao District, Changchun 130032, China.
Zhang Y; Central Laboratory, Changchun Normal University, No. 677 North Changji Road, Erdao District, Changchun 130032, China. Electronic address: zhangyuchi2001@163.com.
Li S; Central Laboratory, Changchun Normal University, No. 677 North Changji Road, Erdao District, Changchun 130032, China.
Liu C; Central Laboratory, Changchun Normal University, No. 677 North Changji Road, Erdao District, Changchun 130032, China. Electronic address: anal_chem@sina.cn.
Zhuang S; Central Laboratory, Changchun Normal University, No. 677 North Changji Road, Erdao District, Changchun 130032, China.
Zhou X; Central Laboratory, Changchun Normal University, No. 677 North Changji Road, Erdao District, Changchun 130032, China.
Li Y; Central Laboratory, Changchun Normal University, No. 677 North Changji Road, Erdao District, Changchun 130032, China.
Liang J; Central Laboratory, Changchun Normal University, No. 677 North Changji Road, Erdao District, Changchun 130032, China.

J Chromatogr B Analyt Technol Biomed Life Sci ; 1209: 123415, 2022 Oct 15.

Article em En | MEDLINE | ID: mdl-35973282

Assuntos

Inibidores de Lipoxigenase; Água; Cromatografia Líquida de Alta Pressão/métodos; Distribuição Contracorrente/métodos; Cetonas; Ligantes; Inibidores de Lipoxigenase/farmacologia; Simulação de Acoplamento Molecular; Phellinus

Palavras-chave

5-lipoxygenase; Combination chromatography; Phellinus igniarius; Response surface methodology; Ultrafiltration

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Água / Inibidores de Lipoxigenase Tipo de estudo: Diagnostic_studies / Screening_studies Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China País de publicação: Holanda

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