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Engineering an autonomous VH domain to modulate intracellular pathways and to interrogate the eIF4F complex.
Frosi, Yuri; Lin, Yen-Chu; Shimin, Jiang; Ramlan, Siti Radhiah; Hew, Kelly; Engman, Alf Henrik; Pillai, Anil; Yeung, Kit; Cheng, Yue Xiang; Cornvik, Tobias; Nordlund, Par; Goh, Megan; Lama, Dilraj; Gates, Zachary P; Verma, Chandra S; Thean, Dawn; Lane, David P; Asial, Ignacio; Brown, Christopher J.
Afiliação
  • Frosi Y; p53 Laboratory (A*STAR), 8A Biomedical Grove, #06-04/05, Neuros/Immunos, 138648, Singapore.
  • Lin YC; Disease Intervention Technology Laboratory (DITL), Institute of Molecular and Cell Biology, A*STAR, Singapore, 138673, Singapore.
  • Shimin J; p53 Laboratory (A*STAR), 8A Biomedical Grove, #06-04/05, Neuros/Immunos, 138648, Singapore.
  • Ramlan SR; Insilico Medicine Taiwan Ltd., Taipei City, 110208, Taiwan.
  • Hew K; Department of Pharmacy, National Yang Ming Chiao Tung University, Taipei City, 112304, Taiwan.
  • Engman AH; p53 Laboratory (A*STAR), 8A Biomedical Grove, #06-04/05, Neuros/Immunos, 138648, Singapore.
  • Pillai A; Disease Intervention Technology Laboratory (DITL), Institute of Molecular and Cell Biology, A*STAR, Singapore, 138673, Singapore.
  • Yeung K; p53 Laboratory (A*STAR), 8A Biomedical Grove, #06-04/05, Neuros/Immunos, 138648, Singapore.
  • Cheng YX; Disease Intervention Technology Laboratory (DITL), Institute of Molecular and Cell Biology, A*STAR, Singapore, 138673, Singapore.
  • Cornvik T; DotBio Pte. Ltd., 1 Research Link, Singapore, 117604, Singapore.
  • Nordlund P; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore, Singapore.
  • Goh M; DotBio Pte. Ltd., 1 Research Link, Singapore, 117604, Singapore.
  • Lama D; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore, Singapore.
  • Gates ZP; DotBio Pte. Ltd., 1 Research Link, Singapore, 117604, Singapore.
  • Verma CS; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore, Singapore.
  • Thean D; DotBio Pte. Ltd., 1 Research Link, Singapore, 117604, Singapore.
  • Lane DP; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore, Singapore.
  • Asial I; DotBio Pte. Ltd., 1 Research Link, Singapore, 117604, Singapore.
  • Brown CJ; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore, Singapore.
Nat Commun ; 13(1): 4854, 2022 08 18.
Article em En | MEDLINE | ID: mdl-35982046

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Iniciação 4E em Eucariotos / Fator de Iniciação 4F em Eucariotos Tipo de estudo: Prognostic_studies Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Singapura

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Iniciação 4E em Eucariotos / Fator de Iniciação 4F em Eucariotos Tipo de estudo: Prognostic_studies Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Singapura