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Increased expression and accumulation of GDF15 in IPF extracellular matrix contribute to fibrosis.
Radwanska, Agata; Cottage, Christopher Travis; Piras, Antonio; Overed-Sayer, Catherine; Sihlbom, Carina; Budida, Ramachandramouli; Wrench, Catherine; Connor, Jane; Monkley, Susan; Hazon, Petra; Schluter, Holger; Thomas, Matthew J; Hogaboam, Cory M; Murray, Lynne A.
Afiliação
  • Radwanska A; Bioscience COPD/IPF, Research and Early Development, Respiratory and Immunology (R&I), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Cottage CT; Bioscience COPD/IPF, Research and Early Development, R&I, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA.
  • Piras A; Bioscience In Vivo, Research and Early Development, R&I, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Overed-Sayer C; Bioscience COPD/IPF, Research and Early Development, R&I, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.
  • Sihlbom C; Proteomics Core Facility of Sahlgrenska Academy, University of Gothenburg, Sweden.
  • Budida R; Translational Science and Experimental Medicine, Research and Early Development, R&I, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Wrench C; Bioscience COPD/IPF, Research and Early Development, R&I, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.
  • Connor J; Bioscience COPD/IPF, Research and Early Development, R&I, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA.
  • Monkley S; Translational Science and Experimental Medicine, Research and Early Development, R&I, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Hazon P; Bioscience COPD/IPF, Research and Early Development, Respiratory and Immunology (R&I), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Schluter H; Bioscience COPD/IPF, Research and Early Development, Respiratory and Immunology (R&I), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Thomas MJ; Bioscience COPD/IPF, Research and Early Development, Respiratory and Immunology (R&I), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Hogaboam CM; Cedar-Sinai, Los Angeles, California, USA.
  • Murray LA; Bioscience COPD/IPF, Research and Early Development, R&I, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.
JCI Insight ; 7(16)2022 08 22.
Article em En | MEDLINE | ID: mdl-35993367
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Matriz Extracelular / Fibrose Pulmonar Idiopática / Fator 15 de Diferenciação de Crescimento Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: JCI Insight Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suécia País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Matriz Extracelular / Fibrose Pulmonar Idiopática / Fator 15 de Diferenciação de Crescimento Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: JCI Insight Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suécia País de publicação: Estados Unidos