Induction of RAC1 protein translation and MKK7/JNK-dependent autophagy through dicer/miR-145/SOX2/miR-365a axis contributes to isorhapontigenin (ISO) inhibition of human bladder cancer invasion.

Hua, Xiaohui; Xiang, Daimin; Guo, Mengxin; Qian, Xiaohui; Chen, Ruifan; Li, Tengda; Tian, Zhongxian; Xu, Jiheng; Huang, Chao; Xie, Qipeng; Huang, Chuanshu

Hua, Xiaohui; Xiang, Daimin; Guo, Mengxin; Qian, Xiaohui; Chen, Ruifan; Li, Tengda; Tian, Zhongxian; Xu, Jiheng; Huang, Chao; Xie, Qipeng; Huang, Chuanshu.

Afiliação

Hua X; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Xiang D; Department of Occupational Health and Environmental Health, School of Public Health, Anhui Medical University, Hefei, Anhui, 230032, China.
Guo M; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Qian X; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Chen R; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Li T; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Tian Z; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Xu J; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Huang C; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Xie Q; Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Huang C; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.

Cell Death Dis ; 13(8): 753, 2022 08 31.

Article em En | MEDLINE | ID: mdl-36045117

Assuntos

MicroRNAs; Neoplasias da Bexiga Urinária; Regiões 3' não Traduzidas; Autofagia/genética; Linhagem Celular Tumoral; RNA Helicases DEAD-box; Regulação Neoplásica da Expressão Gênica; Humanos; MicroRNAs/genética; MicroRNAs/metabolismo; Proteínas Nucleares/metabolismo; Fosforilação; Biossíntese de Proteínas; Ribonuclease III; Fatores de Transcrição SOXB1/metabolismo; Sestrinas; Estilbenos; Neoplasias da Bexiga Urinária/tratamento farmacológico; Neoplasias da Bexiga Urinária/genética; Neoplasias da Bexiga Urinária/metabolismo; Proteínas rac1 de Ligação ao GTP/genética; Proteínas rac1 de Ligação ao GTP/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / MicroRNAs Limite: Humans Idioma: En Revista: Cell Death Dis Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

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