Combined targeting of pathways regulating synaptic formation and autophagy attenuates Alzheimer's disease pathology in mice.

Bjorkli, Christiana; Hemler, Mary; Julian, Joshua B; Sandvig, Axel; Sandvig, Ioanna

Bjorkli, Christiana; Hemler, Mary; Julian, Joshua B; Sandvig, Axel; Sandvig, Ioanna.

Afiliação

Bjorkli C; Department of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
Hemler M; Department of Neurology, St. Olav's Hospital, Trondheim, Norway.
Julian JB; Department of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
Sandvig A; Department of Neurology, St. Olav's Hospital, Trondheim, Norway.
Sandvig I; Princeton Neuroscience Institute, Princeton University, Princeton, NJ, United States.

Front Pharmacol ; 13: 913971, 2022.

Article em En | MEDLINE | ID: mdl-36052130

Palavras-chave

Wnt signalling; amyloid plaques; mTor pathway; microdialysis; neurofibrillary tangles; repurposed drugs

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Pharmacol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Noruega País de publicação: Suíça

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