Lycopene ameliorates hyperlipidemia via potentiation of AMP-activated protein kinase and inhibition of ATP-citrate lyase in diabetic hyperlipidemic rat model.

Elseweidy, Mohamed M; Elawady, Alaa S; Sobh, Mohammed S; Elnagar, Gehad M

Elseweidy, Mohamed M; Elawady, Alaa S; Sobh, Mohammed S; Elnagar, Gehad M.

Afiliação

Elseweidy MM; Department of Biochemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt. Electronic address: mmelseweidy@yahoo.com.
Elawady AS; Department of Biochemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Sobh MS; Pathology Department, Faculty of veterinary medicine, Zagazig University, Zagazig, Egypt.
Elnagar GM; Department of Biochemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.

Life Sci ; 308: 120934, 2022 Nov 01.

Article em En | MEDLINE | ID: mdl-36075470

Assuntos

Diabetes Mellitus; Hiperlipidemias; Proteínas Quinases Ativadas por AMP; ATP Citrato (pro-S)-Liase/metabolismo; Trifosfato de Adenosina; Animais; Atorvastatina/uso terapêutico; Biomarcadores; Coenzima A; Ácido Graxo Sintases; Glutationa; Hiperlipidemias/complicações; Hiperlipidemias/tratamento farmacológico; Hipoglicemiantes/uso terapêutico; Hipolipemiantes/uso terapêutico; Licopeno; Malondialdeído; Complexos Multienzimáticos; Oxo-Ácido-Liases; Ratos; Estreptozocina; Fator de Necrose Tumoral alfa

Palavras-chave

AMPK-P; ATP citrate lyase; Atorvastatin; Hyperlipidemia; Lycopene

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus / Hiperlipidemias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Life Sci Ano de publicação: 2022 Tipo de documento: Article

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