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A humanized 4-1BB-targeting agonistic antibody exerts potent antitumor activity in colorectal cancer without systemic toxicity.
Cheng, Lian-Sheng; Cheng, Yong-Feng; Liu, Wen-Ting; Shen, Aolin; Zhang, Dayan; Xu, Tingjuan; Yin, Wu; Cheng, Min; Ma, Xiaopeng; Wang, Fengrong; Zhao, Qun; Zeng, Xiaoli; Zhang, Yan; Shen, Guodong.
Afiliação
  • Cheng LS; Department of Geriatrics, The First Affiliated Hospital of University of Science and Technology of China, Gerontology Institute of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, Anhui, China.
  • Cheng YF; Hefei HankeMab Biotechnology Limited, Hefei, 230088, Anhui, China.
  • Liu WT; Anhui Provincial Key Laboratory of Tumor Immunotherapy and Nutrition Therapy, Hefei, 230001, Anhui, China.
  • Shen A; Department of Genetics, School of Life Science, Anhui Medical University, Hefei, 230032, Anhui, China.
  • Zhang D; Hefei HankeMab Biotechnology Limited, Hefei, 230088, Anhui, China.
  • Xu T; Anhui Provincial Key Laboratory of Tumor Immunotherapy and Nutrition Therapy, Hefei, 230001, Anhui, China.
  • Yin W; Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, Anhui, China.
  • Cheng M; Hefei HankeMab Biotechnology Limited, Hefei, 230088, Anhui, China.
  • Ma X; Department of Geriatrics, The First Affiliated Hospital of University of Science and Technology of China, Gerontology Institute of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, Anhui, China.
  • Wang F; Anhui Provincial Key Laboratory of Tumor Immunotherapy and Nutrition Therapy, Hefei, 230001, Anhui, China.
  • Zhao Q; Department of Geriatrics, The First Affiliated Hospital of University of Science and Technology of China, Gerontology Institute of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, Anhui, China.
  • Zeng X; Anhui Provincial Key Laboratory of Tumor Immunotherapy and Nutrition Therapy, Hefei, 230001, Anhui, China.
  • Zhang Y; Department of Geriatrics, The First Affiliated Hospital of University of Science and Technology of China, Gerontology Institute of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, Anhui, China.
  • Shen G; Anhui Provincial Key Laboratory of Tumor Immunotherapy and Nutrition Therapy, Hefei, 230001, Anhui, China.
J Transl Med ; 20(1): 415, 2022 09 08.
Article em En | MEDLINE | ID: mdl-36076251
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Membro 9 da Superfamília de Receptores de Fatores de Necrose Tumoral Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Transl Med Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Membro 9 da Superfamília de Receptores de Fatores de Necrose Tumoral Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Transl Med Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido