Synthesis of 4-Hydroxyquinolines as Potential Cytotoxic Agents.

Csuvik, Oszkár; Szemerédi, Nikoletta; Spengler, Gabriella; Szatmári, István

Csuvik, Oszkár; Szemerédi, Nikoletta; Spengler, Gabriella; Szatmári, István.

Afiliação

Csuvik O; Institute of Pharmaceutical Chemistry, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.
Szemerédi N; Department of Medical Microbiology, Albert Szent-Györgyi Health Center and Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis u. 6, H-6725 Szeged, Hungary.
Spengler G; Department of Medical Microbiology, Albert Szent-Györgyi Health Center and Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis u. 6, H-6725 Szeged, Hungary.
Szatmári I; Institute of Pharmaceutical Chemistry, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.

Int J Mol Sci ; 23(17)2022 Aug 26.

Article em En | MEDLINE | ID: mdl-36077085

Assuntos

Adenocarcinoma; Antineoplásicos; Neoplasias do Colo; Hidroxiquinolinas; Antineoplásicos/farmacologia; Compostos de Benzilideno; Citotoxinas; Doxorrubicina/farmacologia; Humanos

Palavras-chave

4-hydroxyquinoline; ConradLimpach reaction; Knoevenagel condensation; cytotoxic effect; modified Mannich reaction; selective toxicity towards MDR cancer

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Adenocarcinoma / Neoplasias do Colo / Hidroxiquinolinas / Antineoplásicos Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Hungria País de publicação: Suíça

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