A Pan-RNase Inhibitor Enabling CRISPR-mRNA Platforms for Engineering of Primary Human Monocytes.

Laoharawee, Kanut; Johnson, Matthew J; Lahr, Walker S; Sipe, Christopher J; Kleinboehl, Evan; Peterson, Joseph J; Lonetree, Cara-Lin; Bell, Jason B; Slipek, Nicholas J; Crane, Andrew T; Webber, Beau R; Moriarity, Branden S

Laoharawee, Kanut; Johnson, Matthew J; Lahr, Walker S; Sipe, Christopher J; Kleinboehl, Evan; Peterson, Joseph J; Lonetree, Cara-Lin; Bell, Jason B; Slipek, Nicholas J; Crane, Andrew T; Webber, Beau R; Moriarity, Branden S.

Afiliação

Laoharawee K; Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA.
Johnson MJ; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.
Lahr WS; Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA.
Sipe CJ; Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA.
Kleinboehl E; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.
Peterson JJ; Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA.
Lonetree CL; Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA.
Bell JB; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.
Slipek NJ; Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA.
Crane AT; Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA.
Webber BR; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.
Moriarity BS; Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA.

Int J Mol Sci ; 23(17)2022 Aug 28.

Article em En | MEDLINE | ID: mdl-36077152

Assuntos

Sistemas CRISPR-Cas; Ribonucleases; Sistemas CRISPR-Cas/genética; Endorribonucleases/genética; Edição de Genes; Técnicas de Inativação de Genes; Engenharia Genética; Humanos; Monócitos; RNA Mensageiro/genética; Ribonucleases/genética

Palavras-chave

CRISPR-Cas9; base editor; genome engineering; pan-RNase inhibitor; primary human monocytes

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ribonucleases / Sistemas CRISPR-Cas Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Suíça

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