A novel homozygous mutation in the PADI6 gene causes early embryo arrest.
Reprod Health
; 19(1): 190, 2022 Sep 10.
Article
em En
| MEDLINE
| ID: mdl-36088419
Some infertile patients experience multiple in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) failure owing to recurrent early embryo arrest. However, the underlying mechanisms remain largely unknown. Due to the development of whole-exome sequencing, early embryo arrest has been confirmed as a type of Mendelian disease. This study aimed to identify the genetic cause of early embryo arrest in patients and to expand the genetic spectrum. Furthermore, it can help doctors offer better suggestions to such patients and prevent patients from suffering from multiple IVF/ICSI failures.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Desenvolvimento Embrionário
/
Proteína-Arginina Desiminase do Tipo 6
/
Infertilidade
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Female
/
Humans
Idioma:
En
Revista:
Reprod Health
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
China
País de publicação:
Reino Unido