A perspective on the discovery of enzyme activators.

Turberville, Antonia; Semple, Hannah; Davies, Gareth; Ivanov, Delyan; Holdgate, Geoffrey A

Turberville, Antonia; Semple, Hannah; Davies, Gareth; Ivanov, Delyan; Holdgate, Geoffrey A.

Afiliação

Turberville A; High-throughput Screening, Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Alderley Park, United Kingdom.
Semple H; High-throughput Screening, Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Alderley Park, United Kingdom.
Davies G; High-throughput Screening, Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Alderley Park, United Kingdom.
Ivanov D; High-throughput Screening, Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Alderley Park, United Kingdom.
Holdgate GA; High-throughput Screening, Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Alderley Park, United Kingdom. Electronic address: geoff.holdgate@astrazeneca.com.

SLAS Discov ; 27(8): 419-427, 2022 12.

Article em En | MEDLINE | ID: mdl-36089246

Assuntos

Ativadores de Enzimas; Ativadores de Enzimas/farmacologia; Ativadores de Enzimas/uso terapêutico

Palavras-chave

Activator; Drug discovery; Enzyme; Enzyme activation; Enzyme kinetics; Mechanism of action; Non-essential activation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ativadores de Enzimas Idioma: En Revista: SLAS Discov Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos

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