Detection of anti-SARS-CoV-2 antibodies and its seroprevalence in Zavidovici municipality of Zenica-Doboj Canton, Bosnia and Herzegovina.
Int J Health Sci (Qassim)
; 16(5): 3-8, 2022.
Article
em En
| MEDLINE
| ID: mdl-36101851
ABSTRACT
Objectives:
Improved serological detection of specific antibodies against SARS-CoV-2 could help estimate the true number of infections.Methods:
A total of 443 serum samples provided by unvaccinated patients of all ages with unknown COVID-19 status that were originally submitted for routine screening or clinical management from outpatient laboratory during the March-April 2021 (third wave) were collected. Seroprevalence of IgM/IgG antibodies was determined by lateral flow immunoassay (Tigsun, Beijing, China).Results:
Among 443 serum samples, 186 (42.0%) were positive (incidence of 5.2/1000) with slight predominace of females, 104 (55.9%), highest seropositivity in 25-50 and 51-64 years age groups, 61 (32.8%) and 57 (30.6%), respectively (P < 0.05); rural population was more prevalent, 101 (54.3%) (P < 0.05) and active workers, 86 (41.1%). Almost equal number of patients was with or without symptoms, 48.4% and 51.6%, respectively. For the comparison, in the same period it was registered 296 (out of 855; 34.6%) PCR SARS-CoV-19 positive persons (incidence of 8.2/1000) with the higher gender (females) and the highest age prevalence in 51-64 years age group (36.8%). In the period March 2020-June 2021, it was registered 804 (out of 3323; 24.2%) (incidence of 22.3/1000) PCR SARS-CoV-19 positive persons with no significant gender and significant age difference (25-50 and 51-64 years group, respectively).Conclusion:
In the regions with high prevalence/incidence of SARS-CoV-2 in the general population (Bosnia and Herzegovina is on the World top on the number of deaths) seroprevalence measuring can help tracking the spread of disease.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Int J Health Sci (Qassim)
Ano de publicação:
2022
Tipo de documento:
Article