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BET inhibition induces vulnerability to MCL1 targeting through upregulation of fatty acid synthesis pathway in breast cancer.
Yan, Gonghong; Luna, Augustin; Wang, Heping; Bozorgui, Behnaz; Li, Xubin; Sanchez, Maga; Dereli, Zeynep; Kahraman, Nermin; Kara, Goknur; Chen, Xiaohua; Zheng, Caishang; McGrail, Daniel; Sahni, Nidhi; Lu, Yiling; Babur, Ozgun; Cokol, Murat; Lim, Bora; Ozpolat, Bulent; Sander, Chris; Mills, Gordon B; Korkut, Anil.
Afiliação
  • Yan G; Department of Bioinformatics and Computational Biology, UT MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Luna A; cBio Center, Department of Data Sciences, Dana Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Wang H; Department of Bioinformatics and Computational Biology, UT MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Bozorgui B; Department of Bioinformatics and Computational Biology, UT MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Li X; Department of Bioinformatics and Computational Biology, UT MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Sanchez M; Department of Bioinformatics and Computational Biology, UT MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Dereli Z; Department of Bioinformatics and Computational Biology, UT MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Kahraman N; Department of Experimental Therapeutics, UT MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Kara G; Department of Experimental Therapeutics, UT MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Chen X; Department of Bioinformatics and Computational Biology, UT MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Zheng C; Department of Bioinformatics and Computational Biology, UT MD Anderson Cancer Center, Houston, TX 77030, USA.
  • McGrail D; Department of Systems Biology, UT MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Sahni N; Department of Bioinformatics and Computational Biology, UT MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Systems Biology, UT MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Epigenetics and Molecular Carcinogenesis, UT MD Anderson Cancer Center, Houston, TX 77030,
  • Lu Y; Department of Genomic Medicine, UT MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Babur O; Computer Science, College of Science and Mathematics, University of Massachusetts Boston, Boston, MA 02125, USA.
  • Cokol M; Axcella Therapeutics, Cambridge, MA 02139, USA.
  • Lim B; Breast Cancer Research Program, Dan L Duncan Comprehensive Cancer Center, Houston, TX 77030, USA.
  • Ozpolat B; Department of Experimental Therapeutics, UT MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Sander C; cBio Center, Department of Data Sciences, Dana Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Mills GB; Department of Cell, Development and Cancer Biology, Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97201, USA.
  • Korkut A; Department of Bioinformatics and Computational Biology, UT MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: akorkut@mdanderson.org.
Cell Rep ; 40(11): 111304, 2022 09 13.
Article em En | MEDLINE | ID: mdl-36103824

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: Cell Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: Cell Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos