Thyroid-stimulating hormone regulates cardiac function through modulating HCN2 via targeting microRNA-1a.

Zhang, Shengjie; Li, Ran; Ma, Yiruo; Yan, Ying; Ma, Mei; Zhang, Keqin; Zhou, Yun; Li, Ling; Pan, Lingling; Ying, Hao; Xue, Ying

Zhang, Shengjie; Li, Ran; Ma, Yiruo; Yan, Ying; Ma, Mei; Zhang, Keqin; Zhou, Yun; Li, Ling; Pan, Lingling; Ying, Hao; Xue, Ying.

Afiliação

Zhang S; Department of Endocrinology and Metabolism, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.
Li R; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Ma Y; Department of Endocrinology and Metabolism, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.
Yan Y; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Ma M; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Zhang K; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Zhou Y; Department of Endocrinology and Metabolism, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.
Li L; Department of Endocrinology and Metabolism, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.
Pan L; Department of Endocrinology and Metabolism, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.
Ying H; Department of Endocrinology and Metabolism, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.
Xue Y; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.

FASEB J ; 36(10): e22561, 2022 10.

Article em En | MEDLINE | ID: mdl-36125044

Assuntos

Canais Disparados por Nucleotídeos Cíclicos Ativados por Hiperpolarização/metabolismo; Hipotireoidismo; MicroRNAs; Canais de Potássio/metabolismo; Animais; Cardiomegalia/metabolismo; Canais Disparados por Nucleotídeos Cíclicos Ativados por Hiperpolarização/genética; Hipotireoidismo/induzido quimicamente; Hipotireoidismo/genética; Camundongos; MicroRNAs/genética; Hormônios Tireóideos; Tireotropina/metabolismo

Palavras-chave

cardiac dysfunction; hyperpolarization-activated cyclic nucleotide-gated channel 2 (HCN2); hypothyroid heart disease; microRNA-1a; thyroid-stimulating hormone (TSH)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Canais de Potássio / MicroRNAs / Canais Disparados por Nucleotídeos Cíclicos Ativados por Hiperpolarização / Hipotireoidismo Limite: Animals Idioma: En Revista: FASEB J Assunto da revista: BIOLOGIA / FISIOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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