SMN controls neuromuscular junction integrity through U7 snRNP.

Tisdale, Sarah; Van Alstyne, Meaghan; Simon, Christian M; Mentis, George Z; Pellizzoni, Livio

Tisdale, Sarah; Van Alstyne, Meaghan; Simon, Christian M; Mentis, George Z; Pellizzoni, Livio.

Afiliação

Tisdale S; Center for Motor Neuron Biology and Disease, Columbia University, New York, NY 10032, USA; Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA; Department of Neurology, Columbia University, New York, NY 10032, USA.
Van Alstyne M; Center for Motor Neuron Biology and Disease, Columbia University, New York, NY 10032, USA; Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA; Department of Neurology, Columbia University, New York, NY 10032, USA.
Simon CM; Center for Motor Neuron Biology and Disease, Columbia University, New York, NY 10032, USA; Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA.
Mentis GZ; Center for Motor Neuron Biology and Disease, Columbia University, New York, NY 10032, USA; Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA; Department of Neurology, Columbia University, New York, NY 10032, USA.
Pellizzoni L; Center for Motor Neuron Biology and Disease, Columbia University, New York, NY 10032, USA; Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA; Department of Neurology, Columbia University, New York, NY 10032, USA. Electronic address: lp2284@cumc.columbia.edu.

Cell Rep ; 40(12): 111393, 2022 09 20.

Article em En | MEDLINE | ID: mdl-36130491

Assuntos

Atrofia Muscular Espinal; Doenças Neurodegenerativas; Agrina/metabolismo; Animais; Histonas/metabolismo; Camundongos; Atrofia Muscular Espinal/metabolismo; Doenças Neurodegenerativas/metabolismo; Junção Neuromuscular/metabolismo; RNA Mensageiro/metabolismo; Ribonucleoproteína Nuclear Pequena U7/química; Ribonucleoproteína Nuclear Pequena U7/metabolismo

Palavras-chave

3'-end mRNA processing; CP: Neuroscience; Lsm proteins; RNP assembly; U7 small nuclear ribonucleoprotein (snRNP); histone gene regulation; motor neurons; neurodegeneration; neuromuscular junction (NMJ); spinal muscular atrophy (SMA); survival motor neuron (SMN)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Atrofia Muscular Espinal / Doenças Neurodegenerativas Limite: Animals Idioma: En Revista: Cell Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

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