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The solution structure of Dead End bound to AU-rich RNA reveals an unusual mode of tandem RRM-RNA recognition required for mRNA regulation.
Duszczyk, Malgorzata M; Wischnewski, Harry; Kazeeva, Tamara; Arora, Rajika; Loughlin, Fionna E; von Schroetter, Christine; Pradère, Ugo; Hall, Jonathan; Ciaudo, Constance; Allain, Frédéric H-T.
Afiliação
  • Duszczyk MM; Institute of Molecular Biology and Biophysics, ETH Zürich, 8093, Zürich, Switzerland. m.m.duszczyk@gmail.com.
  • Wischnewski H; Institute of Molecular Health Sciences, ETH Zürich, 8093, Zürich, Switzerland.
  • Kazeeva T; Institute of Molecular Biology and Biophysics, ETH Zürich, 8093, Zürich, Switzerland.
  • Arora R; Institute of Molecular Health Sciences, ETH Zürich, 8093, Zürich, Switzerland.
  • Loughlin FE; Institute of Molecular Biology and Biophysics, ETH Zürich, 8093, Zürich, Switzerland.
  • von Schroetter C; Monash Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Clayton, 3800, VIC, Australia.
  • Pradère U; Institute of Molecular Biology and Biophysics, ETH Zürich, 8093, Zürich, Switzerland.
  • Hall J; Institute of Biochemistry, Department of Biology, ETH Zürich, 8093, Zürich, Switzerland.
  • Ciaudo C; Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zürich, 8093, Zürich, Switzerland.
  • Allain FH; Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zürich, 8093, Zürich, Switzerland.
Nat Commun ; 13(1): 5892, 2022 10 06.
Article em En | MEDLINE | ID: mdl-36202814

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Motivo de Reconhecimento de RNA Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suíça País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Motivo de Reconhecimento de RNA Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suíça País de publicação: Reino Unido