Your browser doesn't support javascript.
loading
Prioritizing interventions for preventing COVID-19 outbreaks in military basic training.
España, Guido; Perkins, T Alex; Pollett, Simon D; Smith, Morgan E; Moore, Sean M; Kwon, Paul O; Hall, Tara L; Beagle, Milford H; Murray, Clinton K; Hakre, Shilpa; Peel, Sheila A; Modjarrad, Kayvon; Scott, Paul T.
Afiliação
  • España G; Department of Biological Sciences and Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, United States of America.
  • Perkins TA; Department of Biological Sciences and Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, United States of America.
  • Pollett SD; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
  • Smith ME; Department of Biological Sciences and Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, United States of America.
  • Moore SM; Department of Biological Sciences and Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, United States of America.
  • Kwon PO; Moncrief Army Health Clinic, Columbia, South Carolina, United States of America.
  • Hall TL; Moncrief Army Health Clinic, Columbia, South Carolina, United States of America.
  • Beagle MH; United States Army Training Center, Fort Jackson, Columbia, South Carolina, United States of America.
  • Murray CK; Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
  • Hakre S; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
  • Peel SA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, United States of America.
  • Modjarrad K; Diagnostics and Countermeasures Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
  • Scott PT; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
PLoS Comput Biol ; 18(10): e1010489, 2022 10.
Article em En | MEDLINE | ID: mdl-36206315
ABSTRACT
Like other congregate living settings, military basic training has been subject to outbreaks of COVID-19. We sought to identify improved strategies for preventing outbreaks in this setting using an agent-based model of a hypothetical cohort of trainees on a U.S. Army post. Our analysis revealed unique aspects of basic training that require customized approaches to outbreak prevention, which draws attention to the possibility that customized approaches may be necessary in other settings, too. In particular, we showed that introductions by trainers and support staff may be a major vulnerability, given that those individuals remain at risk of community exposure throughout the training period. We also found that increased testing of trainees upon arrival could actually increase the risk of outbreaks, given the potential for false-positive test results to lead to susceptible individuals becoming infected in group isolation and seeding outbreaks in training units upon release. Until an effective transmission-blocking vaccine is adopted at high coverage by individuals involved with basic training, need will persist for non-pharmaceutical interventions to prevent outbreaks in military basic training. Ongoing uncertainties about virus variants and breakthrough infections necessitate continued vigilance in this setting, even as vaccination coverage increases.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: COVID-19 / Militares Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: PLoS Comput Biol Assunto da revista: BIOLOGIA / INFORMATICA MEDICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: COVID-19 / Militares Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: PLoS Comput Biol Assunto da revista: BIOLOGIA / INFORMATICA MEDICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
...