Enhancing intracellular NADPH bioavailability through improving pentose phosphate pathway flux and its application in biocatalysis asymmetric reduction reaction.

Yuan, Lin; Qin, Yan-Li; Zou, Zhi-Cheng; Appiah, Bright; Huang, Hao; Yang, Zhong-Hua; Qun, Can

Yuan, Lin; Qin, Yan-Li; Zou, Zhi-Cheng; Appiah, Bright; Huang, Hao; Yang, Zhong-Hua; Qun, Can.

Afiliação

Yuan L; School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan 430081, China.
Qin YL; School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan 430081, China.
Zou ZC; School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan 430081, China.
Appiah B; School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan 430081, China.
Huang H; School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan 430081, China.
Yang ZH; School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan 430081, China; Key Laboratory of Hubei Province for Coal Conversion and New Carbon Materials, Wuhan University of Science and Technology, Wuhan 430081, China. Electronic address: yangzh@wust.edu.cn.
Qun C; Division of Chemical Metrology and Analytical Science, National Institute of Metrology, Beijing 100029, China.

J Biosci Bioeng ; 134(6): 528-533, 2022 Dec.

Article em En | MEDLINE | ID: mdl-36224065

Assuntos

Escherichia coli; Via de Pentose Fosfato; NADP; Escherichia coli/genética

Palavras-chave

Asymmetric reduction; Chiral alcohol; Cofactor engineering; NADPH; Pentose phosphate pathway; S-4-Chloro-3-hydroxybutylate

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Via de Pentose Fosfato / Escherichia coli Idioma: En Revista: J Biosci Bioeng Assunto da revista: ENGENHARIA BIOMEDICA / MICROBIOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China País de publicação: Japão

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