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Discovery and In Vivo Efficacy of Trace Amine-Associated Receptor 1 (TAAR1) Agonist 4-(2-Aminoethyl)-N-(3,5-dimethylphenyl)piperidine-1-carboxamide Hydrochloride (AP163) for the Treatment of Psychotic Disorders.
Krasavin, Mikhail; Peshkov, Anatoly A; Lukin, Alexey; Komarova, Kristina; Vinogradova, Lyubov; Smirnova, Daria; Kanov, Evgeny V; Kuvarzin, Savelii R; Murtazina, Ramilya Z; Efimova, Evgeniya V; Gureev, Maxim; Onokhin, Kirill; Zakharov, Konstantin; Gainetdinov, Raul R.
Afiliação
  • Krasavin M; Department of Medicinal Chemistry, Institute of Chemistry, Saint Petersburg State University, Saint Petersburg 199034, Russia.
  • Peshkov AA; Department of Medicinal Chemistry, Institute of Chemistry, Saint Petersburg State University, Saint Petersburg 199034, Russia.
  • Lukin A; Lomonosov Institute of Fine Chemical Technologies, MIREA-Russian Technological University, Moscow 119454, Russia.
  • Komarova K; Lomonosov Institute of Fine Chemical Technologies, MIREA-Russian Technological University, Moscow 119454, Russia.
  • Vinogradova L; Lomonosov Institute of Fine Chemical Technologies, MIREA-Russian Technological University, Moscow 119454, Russia.
  • Smirnova D; Department of Medicinal Chemistry, Institute of Chemistry, Saint Petersburg State University, Saint Petersburg 199034, Russia.
  • Kanov EV; Institute of Translational Biomedicine, Saint Petersburg State University, Saint Petersburg 199034, Russia.
  • Kuvarzin SR; Institute of Translational Biomedicine, Saint Petersburg State University, Saint Petersburg 199034, Russia.
  • Murtazina RZ; Institute of Translational Biomedicine, Saint Petersburg State University, Saint Petersburg 199034, Russia.
  • Efimova EV; Institute of Translational Biomedicine, Saint Petersburg State University, Saint Petersburg 199034, Russia.
  • Gureev M; Center of Bio- and Chemoinformatics, Sechenov First Moscow State Medical University, Moscow 119435, Russia.
  • Onokhin K; Institute of Translational Biomedicine, Saint Petersburg State University, Saint Petersburg 199034, Russia.
  • Zakharov K; Accellena Research and Development Inc., 88A Sredniy pr. V.O., Saint Petersburg 199106, Russia.
  • Gainetdinov RR; Institute of Translational Biomedicine, Saint Petersburg State University, Saint Petersburg 199034, Russia.
Int J Mol Sci ; 23(19)2022 Sep 30.
Article em En | MEDLINE | ID: mdl-36232878
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos Psicóticos / Proteínas da Membrana Plasmática de Transporte de Dopamina Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Revista: Int J Mol Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Federação Russa País de publicação: Suíça
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos Psicóticos / Proteínas da Membrana Plasmática de Transporte de Dopamina Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Revista: Int J Mol Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Federação Russa País de publicação: Suíça