Human Papillary and Reticular Fibroblasts Show Distinct Functions on Tumor Behavior in 3D-Organotypic Cultures Mimicking Melanoma and HNSCC.

Wu, Shidi; Rietveld, Marion; Hogervorst, Marieke; de Gruijl, Frank; van der Burg, Sjoerd; Vermeer, Maarten; van Doorn, Remco; Welters, Marij; El Ghalbzouri, Abdoelwaheb

Wu, Shidi; Rietveld, Marion; Hogervorst, Marieke; de Gruijl, Frank; van der Burg, Sjoerd; Vermeer, Maarten; van Doorn, Remco; Welters, Marij; El Ghalbzouri, Abdoelwaheb.

Afiliação

Wu S; Department of Dermatology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Rietveld M; Department of Dermatology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Hogervorst M; Department of Dermatology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
de Gruijl F; Department of Dermatology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
van der Burg S; Department of Medical Oncology, Oncode Institude, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Vermeer M; Department of Dermatology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
van Doorn R; Department of Dermatology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Welters M; Department of Medical Oncology, Oncode Institude, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
El Ghalbzouri A; Department of Dermatology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.

Int J Mol Sci ; 23(19)2022 Oct 01.

Article em En | MEDLINE | ID: mdl-36232952

Assuntos

Carcinoma de Células Escamosas; Neoplasias de Cabeça e Pescoço; Melanoma; Neoplasias Cutâneas; Biomarcadores/metabolismo; Carcinoma de Células Escamosas/patologia; Linhagem Celular Tumoral; Transição Epitelial-Mesenquimal/genética; Fibroblastos/metabolismo; Neoplasias de Cabeça e Pescoço/patologia; Humanos; Melanoma/metabolismo; Neoplasias Cutâneas/patologia; Carcinoma de Células Escamosas de Cabeça e Pescoço/patologia

Palavras-chave

EMT; HNSCC; cancer-associated fibroblast; melanoma; papillary fibroblast; reticular fibroblast; tumor invasion; tumor microenvironment

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Carcinoma de Células Escamosas / Neoplasias de Cabeça e Pescoço / Melanoma Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda

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