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Systematic Mendelian randomization using the human plasma proteome to discover potential therapeutic targets for stroke.
Chen, Lingyan; Peters, James E; Prins, Bram; Persyn, Elodie; Traylor, Matthew; Surendran, Praveen; Karthikeyan, Savita; Yonova-Doing, Ekaterina; Di Angelantonio, Emanuele; Roberts, David J; Watkins, Nicholas A; Ouwehand, Willem H; Danesh, John; Lewis, Cathryn M; Bronson, Paola G; Markus, Hugh S; Burgess, Stephen; Butterworth, Adam S; Howson, Joanna M M.
Afiliação
  • Chen L; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Peters JE; Department of Genetics, Novo Nordisk Research Centre Oxford, Oxford, UK.
  • Prins B; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Persyn E; Department of Immunology and Inflammation, Faculty of Medicine, Imperial College London, London, UK.
  • Traylor M; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Surendran P; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Karthikeyan S; Department of Medical and Molecular Genetics, King's College London, London, UK.
  • Yonova-Doing E; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Di Angelantonio E; Department of Genetics, Novo Nordisk Research Centre Oxford, Oxford, UK.
  • Roberts DJ; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, UK.
  • Watkins NA; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Ouwehand WH; Rutherford Fund Fellow, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, Cambridge, UK.
  • Danesh J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Lewis CM; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Bronson PG; Department of Genetics, Novo Nordisk Research Centre Oxford, Oxford, UK.
  • Markus HS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Burgess S; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.
  • Butterworth AS; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.
  • Howson JMM; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.
Nat Commun ; 13(1): 6143, 2022 10 17.
Article em En | MEDLINE | ID: mdl-36253349
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrilação Atrial / Acidente Vascular Cerebral / Diabetes Mellitus Tipo 2 Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrilação Atrial / Acidente Vascular Cerebral / Diabetes Mellitus Tipo 2 Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de publicação: Reino Unido