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Impact of Parity on Cardiac Structure and Function in Apparently Healthy Pregnant Nigerian Women.
Saidu, H; Mohammed, I Y; Ishaq, N A; Balarabe, S A; Tukur, J; Adedeji, T A; Makinde, O N; Adebayo, R A; Umar, H; Isezuo, S A; Karaye, K M.
Afiliação
  • Saidu H; Department of Medicine, Bayero University, Kano, Kano State, Nigeria.
  • Mohammed IY; Department of Medicine, Murtala Mohammed Specialist Hospital, Kano, Kano State, Nigeria.
  • Ishaq NA; Department of Medicine, Bayero University, Kano, Kano State, Nigeria.
  • Balarabe SA; Department of Medicine, Aminu Kano Teaching Hospital, Kano, Kano State, Nigeria.
  • Tukur J; Department of Medicine, Aminu Kano Teaching Hospital, Kano, Kano State, Nigeria.
  • Adedeji TA; Department of Medicine, Mohammed Abdullahi Wase Specialist Hospital, Kano, Kano State, Nigeria.
  • Makinde ON; Department of Medicine, Bayero University, Kano, Kano State, Nigeria.
  • Adebayo RA; Department of Medicine, Aminu Kano Teaching Hospital, Kano, Kano State, Nigeria.
  • Umar H; Department of Chemical Pathology, Obafemi Awolowo University Teaching Hospitals Complex, Ile Ife, Osun State, Nigeria.
  • Isezuo SA; Department of Obstetrics and Gynaecology, Obafemi Awolowo University Teaching Hospitals Complex, Ile Ife, Osun State, Nigeria.
  • Karaye KM; Department of Medicine, Obafemi Awolowo University Teaching Hospitals Complex, Ile Ife, Osun State, Nigeria.
West Afr J Med ; 39(10): 1057-1061, 2022 Oct 20.
Article em En | MEDLINE | ID: mdl-36260810
ABSTRACT

BACKGROUND:

There are few and conflicting reports in the literature about the relationship between parity and maternal cardiac function. The study aimed to assess the impact of parity on cardiac structure and function in apparently healthy pregnant women in Nigeria.

METHODS:

This was a cross-sectional study carried out in 3 tertiary centers in Kano, and 1 in Ile-Ife, Nigeria. 112 apparently healthy pregnant women were consecutively recruited between the 28th and 38th weeks of gestation, and their cardiac structure and function assessed using echocardiography. Left ventricular (LV) systolic dysfunction was defined as LV ejection fraction of below 50%, and diastolic dysfunction was graded using mitral filling and tissue Doppler velocities.

RESULTS:

LV systolic dysfunction and diastolic dysfunction were found in 6 (5.4%) subjects and 20 (17.9%) subjects, respectively. Age (p= <0.0001), left atrial (LA) size (P<0.0001), interventricular septal thickness at end diastole (IVSD) (p= 0.005), posterior wall thickness at end diastole (PWTD) (p=0.004) and QRS duration (p= <0.0001) all increased progressively with higher parity, while tricuspid annular systolic excursion (p=0.320) decreased with higher parity. There was significant positive correlation between parity and age (r= 0.475, p= <0.0001), LA size (r=0.332, p= <0.0001), IVSD (r=0.264, p= 0.005) and PWTD (r= 0.343, p= <0.0001). LV systolic function was not significantly associated with parity.

CONCLUSION:

Our findings suggested that parity was significantly associated with myocardial remodeling in apparently healthy pregnant women.
CONTEXTE Il existe peu de données contradictoires dans la littérature sur la relation entre la parité et la fonction cardiaque maternelle. L'étude visait à évaluer l'impact de la parité sur la structure et la fonction cardiaques chez des femmes enceintes apparemment en bonne santé au Nigeria. METHODES Il s'agissait d'une étude transversale menée dans 3 centres tertiaires à Kano et 1 à Ile-Ife, au Nigeria. 112 femmes enceintes apparemment en bonne santé ont été recrutées consécutivement entre la 28* et la 38* semaine de gestation, et leur structure et fonction cardiaques ont été évaluées par échocardiographie. La dysfonction systolique du ventricule gauche (VG) a été définie comme une fraction d'éjection du VG inférieure à 50 %, et la dysfonction diastolique a été graduée en utilisant le remplissage mitral et les vitesses Doppler tissulaires. RESULTATS Un dysfonctionnement systolique VG et un dysfonctionnement diastolique ont été trouvés chez 6 (5,4 %) sujets et 20 (17,9 %) sujets respectivement. Âge (p=<0,0001), taille de l'oreillette gauche (LA) (P<0,0001), épaisseur du septum interventriculaire en fin de diastole (IVSD) (p=0,005), épaisseur de la paroi postérieure en fin de diastole (PWTD)(p=0,004) et La durée du QRS (p = <0,0001) a augmenté progressivement avec une parité plus élevée, tandis que l'excursion systolique annulaire tricuspide (p = 0,320) a diminué avec une parité plus élevée. Il y avait une corrélation positive significative entre la parité et l'âge (r = 0,475, p = <0,0001), la taille LA (r = 0,332, p = <0,0001), IVSD (r = 0,264, p = 0,005) et PWTD (r = 0,343, p=<0,0001). La fonction systolique VG était associée à la parité.

CONCLUSION:

Nos résultats suggèrent que la parité est significativement associée au remodelage du myocarde chez les femmes enceintes apparemment en bonne santé. n'était pas significatif. Mots clés Grossesse, Parité, Structure Cardiaque, Registre peace.
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Disfunção Ventricular Esquerda / Gestantes Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Female / Humans / Pregnancy País/Região como assunto: Africa Idioma: En Revista: West Afr J Med Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Nigéria
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Disfunção Ventricular Esquerda / Gestantes Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Female / Humans / Pregnancy País/Região como assunto: Africa Idioma: En Revista: West Afr J Med Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Nigéria