A recommendation on the teaching of Michaelis-Menten kinetics in biochemistry courses.

ABSTRACT

Most textbooks and lecturers present Michaelis-Menten kinetics using the equation v = Vmax [S]/(Km  + [S]). There are advantages to presenting this relationship in a slightly different form, namely v = Vmax /{1 + (Km /[S])}. We articulate advantages for single-substrate reactions and extend the formalism to include the three classes of bi-substrate reactions.