Pharmacological inhibition of the acetyltransferase Tip60 mitigates myocardial infarction injury.

Wang, Xinrui; Wan, Tina C; Kulik, Katherine R; Lauth, Amelia; Smith, Brian C; Lough, John W; Auchampach, John A

Wang, Xinrui; Wan, Tina C; Kulik, Katherine R; Lauth, Amelia; Smith, Brian C; Lough, John W; Auchampach, John A.

Afiliação

Wang X; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Wan TC; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Kulik KR; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Lauth A; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Smith BC; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Lough JW; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Auchampach JA; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

Dis Model Mech ; 16(5)2023 05 01.

Article em En | MEDLINE | ID: mdl-36341679

Assuntos

Histona Acetiltransferases; Infarto do Miocárdio; Camundongos; Animais; Histona Acetiltransferases/metabolismo; Apoptose; Miócitos Cardíacos/metabolismo; Histonas/metabolismo; Infarto do Miocárdio/tratamento farmacológico

Palavras-chave

Apoptosis; Cardiomyocyte proliferation; Cardioprotection; Cell-cycle activation; Myocardial infarction; Regeneration; TH1834; Tip60

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Histona Acetiltransferases / Infarto do Miocárdio Limite: Animals Idioma: En Revista: Dis Model Mech Assunto da revista: MEDICINA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido

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