Effects of Alpinae Oxyphyllae Fructus on microglial polarization in a LPS-induced BV2 cells model of neuroinflammation via TREM2.

Xu, Mengjie; Yang, Yunfang; Peng, Jing; Zhang, Yue; Wu, Bo; He, Bosai; Jia, Ying; Yan, Tingxu

Xu, Mengjie; Yang, Yunfang; Peng, Jing; Zhang, Yue; Wu, Bo; He, Bosai; Jia, Ying; Yan, Tingxu.

Afiliação

Xu M; Department of Biological Sciences, XinZhou Teachers University, DunQi Street 1, Xinzhou, 034000, China.
Yang Y; School of Functional Food and Wine, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, China.
Peng J; School of Functional Food and Wine, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, China.
Zhang Y; School of Functional Food and Wine, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, China.
Wu B; School of Functional Food and Wine, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, China.
He B; School of Functional Food and Wine, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, China.
Jia Y; School of Functional Food and Wine, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, China. Electronic address: jysyphu@163.com.
Yan T; School of Functional Food and Wine, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, China. Electronic address: ytxsyphu@163.com.

J Ethnopharmacol ; 302(Pt A): 115914, 2023 Feb 10.

Article em En | MEDLINE | ID: mdl-36347303

Assuntos

Lipopolissacarídeos; Microglia; Humanos; Lipopolissacarídeos/farmacologia; Interleucina-10/metabolismo; Receptor 4 Toll-Like/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Fator de Necrose Tumoral alfa/metabolismo; Glicogênio Sintase Quinase 3 beta/metabolismo; RNA Interferente Pequeno/farmacologia; Simulação de Acoplamento Molecular; Fator Neurotrófico Derivado do Encéfalo/metabolismo; Glicoproteínas de Membrana/metabolismo; Receptores Imunológicos/genética; Receptores Imunológicos/metabolismo

Palavras-chave

Alpinae oxyphyllae fructus; Alzheimer's disease; Chrysin; Microglia phenotype; TREM2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lipopolissacarídeos / Microglia Limite: Humans Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China País de publicação: Irlanda

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