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Single-Cell Transcriptomics Reveals Longevity Immune Remodeling Features Shared by Centenarians and Their Offspring.
Dong, Chen; Miao, Ya-Ru; Zhao, Rui; Yang, Mei; Guo, An-Yuan; Xue, Zhong-Hui; Li, Teng; Zhang, Qiong; Bao, Yanfeng; Shen, Chen; Sun, Chi; Yang, Ying; Gu, Xi-Xi; Jin, Yi; Li, Rong; Xu, Min; Guo, Jia-Xin; Zong, Zhi-Ying; Zhou, Wei; He, Mei; Wang, Dan-Ni; Su, Jian-You; Zhang, Xiao-Ming; Zeng, Xu-Hui; Gao, Jian-Lin; Gu, Zhi-Feng.
Afiliação
  • Dong C; Research Center of Clinical Medicine, Research Center of Gerontology and Longevity, Key Laboratory of Immunology, Research Center of Nursing, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Miao YR; Center for Artificial Intelligence Biology, Hubei Bioinformatics & Molecular Imaging Key Laboratory, Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China.
  • Zhao R; Research Center of Clinical Medicine, Research Center of Gerontology and Longevity, Key Laboratory of Immunology, Research Center of Nursing, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Yang M; Center for Artificial Intelligence Biology, Hubei Bioinformatics & Molecular Imaging Key Laboratory, Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China.
  • Guo AY; Research Center of Clinical Medicine, Research Center of Gerontology and Longevity, Key Laboratory of Immunology, Research Center of Nursing, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Xue ZH; Center for Artificial Intelligence Biology, Hubei Bioinformatics & Molecular Imaging Key Laboratory, Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China.
  • Li T; Research Center of Clinical Medicine, Research Center of Gerontology and Longevity, Key Laboratory of Immunology, Research Center of Nursing, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Zhang Q; Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 200025, China.
  • Bao Y; Research Center of Clinical Medicine, Research Center of Gerontology and Longevity, Key Laboratory of Immunology, Research Center of Nursing, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Shen C; Research Center of Clinical Medicine, Research Center of Gerontology and Longevity, Key Laboratory of Immunology, Research Center of Nursing, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Sun C; Research Center of Clinical Medicine, Research Center of Gerontology and Longevity, Key Laboratory of Immunology, Research Center of Nursing, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Yang Y; Department of Geriatrics, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Gu XX; Research Center of Clinical Medicine, Research Center of Gerontology and Longevity, Key Laboratory of Immunology, Research Center of Nursing, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Jin Y; Research Center of Clinical Medicine, Research Center of Gerontology and Longevity, Key Laboratory of Immunology, Research Center of Nursing, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Li R; Research Center of Clinical Medicine, Research Center of Gerontology and Longevity, Key Laboratory of Immunology, Research Center of Nursing, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Xu M; Research Center of Clinical Medicine, Research Center of Gerontology and Longevity, Key Laboratory of Immunology, Research Center of Nursing, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Guo JX; Research Center of Clinical Medicine, Research Center of Gerontology and Longevity, Key Laboratory of Immunology, Research Center of Nursing, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Zong ZY; Research Center of Clinical Medicine, Research Center of Gerontology and Longevity, Key Laboratory of Immunology, Research Center of Nursing, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Zhou W; Research Center of Clinical Medicine, Research Center of Gerontology and Longevity, Key Laboratory of Immunology, Research Center of Nursing, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • He M; Research Center of Clinical Medicine, Research Center of Gerontology and Longevity, Key Laboratory of Immunology, Research Center of Nursing, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Wang DN; Research Center of Clinical Medicine, Research Center of Gerontology and Longevity, Key Laboratory of Immunology, Research Center of Nursing, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Su JY; Research Center of Clinical Medicine, Research Center of Gerontology and Longevity, Key Laboratory of Immunology, Research Center of Nursing, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Zhang XM; Laboratory Center, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Zeng XH; Research Center of Clinical Medicine, Research Center of Gerontology and Longevity, Key Laboratory of Immunology, Research Center of Nursing, Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
  • Gao JL; Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 200025, China.
  • Gu ZF; Institute of Reproductive Medicine, Medical School, Nantong University, Nantong, 226001, China.
Adv Sci (Weinh) ; 9(36): e2204849, 2022 12.
Article em En | MEDLINE | ID: mdl-36354175

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucócitos Mononucleares / Centenários Tipo de estudo: Prognostic_studies Limite: Aged80 / Humans Idioma: En Revista: Adv Sci (Weinh) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucócitos Mononucleares / Centenários Tipo de estudo: Prognostic_studies Limite: Aged80 / Humans Idioma: En Revista: Adv Sci (Weinh) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China