Plasma RNA profiling unveils transcriptional signatures associated with resistance to osimertinib in EGFR T790M positive non-small cell lung cancer patients.

Alexeyenko, Andrey; Brustugun, Odd Terje; Eide, Inger Johanne Zwicky; Gencheva, Radosveta; Kosibaty, Zeinab; Lai, Yi; de Petris, Luigi; Tsakonas, Georgios; Grundberg, Oscar; Franzen, Bo; Viktorsson, Kristina; Lewensohn, Rolf; Hydbring, Per; Ekman, Simon

Alexeyenko, Andrey; Brustugun, Odd Terje; Eide, Inger Johanne Zwicky; Gencheva, Radosveta; Kosibaty, Zeinab; Lai, Yi; de Petris, Luigi; Tsakonas, Georgios; Grundberg, Oscar; Franzen, Bo; Viktorsson, Kristina; Lewensohn, Rolf; Hydbring, Per; Ekman, Simon.

Afiliação

Alexeyenko A; Science for Life Laboratory, Box 1031, Solna, Sweden.
Brustugun OT; Evi-networks consulting, Huddinge, Sweden.
Eide IJZ; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden.
Gencheva R; Section of Oncology, Drammen Hospital, Vestre Viken Hospital Trust, Drammen, Norway.
Kosibaty Z; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Lai Y; Department of Cancer Genetics, Institute for Cancer Research, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.
de Petris L; Section of Oncology, Drammen Hospital, Vestre Viken Hospital Trust, Drammen, Norway.
Tsakonas G; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Grundberg O; Department of Cancer Genetics, Institute for Cancer Research, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.
Franzen B; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.
Viktorsson K; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.
Lewensohn R; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.
Hydbring P; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.
Ekman S; Thoracic Oncology Center, Karolinska University Hospital, Stockholm, Sweden.

Transl Lung Cancer Res ; 11(10): 2064-2078, 2022 Oct.

Article em En | MEDLINE | ID: mdl-36386450

Palavras-chave

Non-small cell lung cancer (NSCLC); epidermal growth factor receptor (EGFR); exosomal RNA; osimertinib; transcriptome

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Risk_factors_studies Idioma: En Revista: Transl Lung Cancer Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suécia País de publicação: China

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