Stable binding to phosphatidylserine-containing membranes requires conserved arginine residues in tandem C domains of blood coagulation factor VIII.

Peters, Shaun C; Childers, Kenneth C; Mitchell, Corbin E; Avery, Nathan G; Reese, Steven S; Mitchell, Cristopher; Wo, Serena W; Swanson, Christopher D; Brison, Caileen M; Spiegel, P Clint

Peters, Shaun C; Childers, Kenneth C; Mitchell, Corbin E; Avery, Nathan G; Reese, Steven S; Mitchell, Cristopher; Wo, Serena W; Swanson, Christopher D; Brison, Caileen M; Spiegel, P Clint.

Afiliação

Peters SC; Department of Chemistry, Western Washington University, Bellingham, WA, United States.
Childers KC; Department of Chemistry, Western Washington University, Bellingham, WA, United States.
Mitchell CE; Department of Chemistry, Western Washington University, Bellingham, WA, United States.
Avery NG; Department of Chemistry, Western Washington University, Bellingham, WA, United States.
Reese SS; Department of Chemistry, Western Washington University, Bellingham, WA, United States.
Mitchell C; Department of Chemistry, Western Washington University, Bellingham, WA, United States.
Wo SW; Department of Chemistry, Western Washington University, Bellingham, WA, United States.
Swanson CD; Department of Chemistry, Western Washington University, Bellingham, WA, United States.
Brison CM; Department of Chemistry, Western Washington University, Bellingham, WA, United States.
Spiegel PC; Department of Chemistry, Western Washington University, Bellingham, WA, United States.

Front Mol Biosci ; 9: 1040106, 2022.

Article em En | MEDLINE | ID: mdl-36387287

Palavras-chave

X-ray crystallography; antibody inhibitors; blood coagulation; factor VIII; membrane binding

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Front Mol Biosci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Suíça

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