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New Insights into Melanoma Tumor Syndromes.
Rashid, Sarem; Gupta, Sameer; McCormick, Shelley R; Tsao, Hensin.
Afiliação
  • Rashid S; Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Gupta S; Boston University School of Medicine, Boston, Massachusetts, USA.
  • McCormick SR; Department of Dermatology, The Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA.
  • Tsao H; Mass General Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
JID Innov ; 2(6): 100152, 2022 Nov.
Article em En | MEDLINE | ID: mdl-36387771
Melanoma tumor syndromes (MTS) represent an important minority of familial melanoma cases. In these patients, the accumulation of sequence alterations in essential genes may prelude the risk of internal malignancies, in addition to melanoma. Although several host and environmental factors have been implicated in familial melanoma, the exact mechanisms of cancer predisposition-particularly in the context of mixed cancer syndromes-still remain unclear. In this paper, we review new insights into MTS and elucidate recent efforts that guide individualized prognostication and treatment for these diseases in the past quarter century.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: JID Innov Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: JID Innov Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Holanda