Cooperative binding of T cell receptor and CD4 to peptide-MHC enhances antigen sensitivity.

Rushdi, Muaz Nik; Pan, Victor; Li, Kaitao; Choi, Hyun-Kyu; Travaglino, Stefano; Hong, Jinsung; Griffitts, Fletcher; Agnihotri, Pragati; Mariuzza, Roy A; Ke, Yonggang; Zhu, Cheng

Rushdi, Muaz Nik; Pan, Victor; Li, Kaitao; Choi, Hyun-Kyu; Travaglino, Stefano; Hong, Jinsung; Griffitts, Fletcher; Agnihotri, Pragati; Mariuzza, Roy A; Ke, Yonggang; Zhu, Cheng.

Afiliação

Rushdi MN; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA.
Pan V; Parker H. Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA, USA.
Li K; Medtronic CO., Minneapolis, MN, USA.
Choi HK; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA.
Travaglino S; Parker H. Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA, USA.
Hong J; Intellia Therapeutics, Cambridge, MA, USA.
Griffitts F; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA.
Agnihotri P; Parker H. Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA, USA.
Mariuzza RA; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA.
Ke Y; Parker H. Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA, USA.
Zhu C; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA.

Nat Commun ; 13(1): 7055, 2022 11 17.

Article em En | MEDLINE | ID: mdl-36396644

Assuntos

Antígenos; Receptores de Antígenos de Linfócitos T; Receptores de Antígenos de Linfócitos T/metabolismo; Complexo Principal de Histocompatibilidade; Antígenos de Histocompatibilidade; Peptídeos/química

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T / Antígenos Tipo de estudo: Diagnostic_studies Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido

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