Connective tissue disease-related interstitial lung disease is alleviated by tripterine through inhibition of the PI3K/Akt, apoptosis, and TNF-&#945; signalling pathways.

Zhu, Wen; Wang, Yifan; Liu, Chenxi; Wu, Yunxia; Li, Yehui; Wang, Yue

Connective tissue disease-related interstitial lung disease is alleviated by tripterine through inhibition of the PI3K/Akt, apoptosis, and TNF-α signalling pathways.

Zhu, Wen; Wang, Yifan; Liu, Chenxi; Wu, Yunxia; Li, Yehui; Wang, Yue.

Afiliação

Zhu W; Institute of Rheumatology, Nanjing University of Chinese Medicine, Nanjing, China.
Wang Y; Institute of Rheumatology, Nanjing University of Chinese Medicine, Nanjing, China.
Liu C; Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
Wu Y; Institute of Rheumatology, Nanjing University of Chinese Medicine, Nanjing, China.
Li Y; Institute of Rheumatology, Nanjing University of Chinese Medicine, Nanjing, China.
Wang Y; Department of Rheumatology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.

Front Pharmacol ; 13: 990760, 2022.

Article em En | MEDLINE | ID: mdl-36419618

Palavras-chave

CTD-ILD; PI3K/AKT; apoptosis; molecular docking; network pharmacology; tripterine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Front Pharmacol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China País de publicação: Suíça

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