T1 mapping and reduced field-of-view DWI at 3.0 T MRI for differentiation of thyroid papillary carcinoma from nodular goiter.
Clin Physiol Funct Imaging
; 43(3): 137-145, 2023 May.
Article
em En
| MEDLINE
| ID: mdl-36440541
ABSTRACT
BACKGROUND:
Reduced field-of-view diffusion-weighted imaging (rFOV-DWI) could be proved to quantitatively identify papillary thyroid carcinoma (PTC) and there is no literature regarding the use of T1 mapping to distinguish nodular goiter (NG) from PTC.PURPOSE:
To compare T1 mapping with rFOV-DWI in differentiating NG and PTC. STUDY TYPE Prospective study. POPULATIONS Ninety-five hospitalized patients with thyroid nodules were included in the research. SEQUENCE All subjects underwent T1-weighted imaging, T2-weighted imaging, rFOV-DWI and T1-mapping sequences. ASSESSMENT The apparent diffusion coefficient (ADC) and T1 values of each thyroid nodule were measured, respectively. According to pathological results, the thyroid nodules were divided into two groups Group 1 (NG) and Group 2 (PTC). STATISTICAL TESTS An independent sample t test was used to evaluate the differences of ADC and T1 between the two groups. The receiver operating characteristic (ROC) curve was used to analyze the diagnostic efficiency of T1, ADC, Thyroid Imaging Reporting and Data System (TI-RADS) and T1 and ADC.RESULTS:
The T1 and ADC values of nodular goiter were both higher than those of PTC (p < 0.05). The area under the ROC curve (AUC) values of T1 and ADC were significantly higher than that of T1 or ADC alone (p < 0.05). The AUC value of T1 and ADC was as same as that of TI-RADS.CONCLUSION:
The combination of T1 mapping and rFOV-DWI could effectively differentiate NG from PTC. And it has at least the same diagnostic value as the ultrasound-based TI-RADS classification.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Glândula Tireoide
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Carcinoma Papilar
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Nódulo da Glândula Tireoide
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Bócio Nodular
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Clin Physiol Funct Imaging
Assunto da revista:
FISIOLOGIA
/
PATOLOGIA
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
China
País de publicação:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
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UK
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UNITED KINGDOM