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Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential.
Kneppers, Jeroen; Severson, Tesa M; Siefert, Joseph C; Schol, Pieter; Joosten, Stacey E P; Yu, Ivan Pak Lok; Huang, Chia-Chi Flora; Morova, Tunç; Altintas, Umut Berkay; Giambartolomei, Claudia; Seo, Ji-Heui; Baca, Sylvan C; Carneiro, Isa; Emberly, Eldon; Pasaniuc, Bogdan; Jerónimo, Carmen; Henrique, Rui; Freedman, Matthew L; Wessels, Lodewyk F A; Lack, Nathan A; Bergman, Andries M; Zwart, Wilbert.
Afiliação
  • Kneppers J; Division of Oncogenomics, Oncode Institute, Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Severson TM; Division of Oncogenomics, Oncode Institute, Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Siefert JC; Division of Molecular Carcinogenesis, Oncode Institute, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Schol P; Division of Oncogenomics, Oncode Institute, Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Joosten SEP; Division of Molecular Carcinogenesis, Oncode Institute, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Yu IPL; Division of Oncogenomics, Oncode Institute, Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Huang CF; Division of Oncogenomics, Oncode Institute, Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Morova T; Vancouver Prostate Centre, Department of Urologic Science, University of British Columbia, Vancouver, Canada.
  • Altintas UB; Vancouver Prostate Centre, Department of Urologic Science, University of British Columbia, Vancouver, Canada.
  • Giambartolomei C; Vancouver Prostate Centre, Department of Urologic Science, University of British Columbia, Vancouver, Canada.
  • Seo JH; School of Medicine, Koç University, Istanbul, Turkey.
  • Baca SC; Central RNA Lab, Istituto Italiano di Tecnologia, Genova, Italy.
  • Carneiro I; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, USA.
  • Emberly E; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, USA.
  • Pasaniuc B; The Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, USA.
  • Jerónimo C; The Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, USA.
  • Henrique R; Department of Pathology, Cancer Biology and Epigenetics Group, Portuguese Oncology Institute of Porto and Porto Comprehensive Cancer Center, Porto, Portugal.
  • Freedman ML; Department of Physics, Simon Fraser University, Burnaby, Canada.
  • Wessels LFA; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, USA.
  • Lack NA; Department of Pathology, Cancer Biology and Epigenetics Group, Portuguese Oncology Institute of Porto and Porto Comprehensive Cancer Center, Porto, Portugal.
  • Bergman AM; Department of Pathology, Cancer Biology and Epigenetics Group, Portuguese Oncology Institute of Porto and Porto Comprehensive Cancer Center, Porto, Portugal.
  • Zwart W; The Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, USA.
Nat Commun ; 13(1): 7367, 2022 11 30.
Article em En | MEDLINE | ID: mdl-36450752
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Receptores Androgênicos Limite: Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Receptores Androgênicos Limite: Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda País de publicação: Reino Unido