An in silico method to assess antibody fragment polyreactivity.

Harvey, Edward P; Shin, Jung-Eun; Skiba, Meredith A; Nemeth, Genevieve R; Hurley, Joseph D; Wellner, Alon; Shaw, Ada Y; Miranda, Victor G; Min, Joseph K; Liu, Chang C; Marks, Debora S; Kruse, Andrew C

Harvey, Edward P; Shin, Jung-Eun; Skiba, Meredith A; Nemeth, Genevieve R; Hurley, Joseph D; Wellner, Alon; Shaw, Ada Y; Miranda, Victor G; Min, Joseph K; Liu, Chang C; Marks, Debora S; Kruse, Andrew C.

Afiliação

Harvey EP; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, 02115, USA.
Shin JE; Department of Systems Biology, Harvard Medical School, Boston, MA, 02115, USA.
Skiba MA; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, 02115, USA.
Nemeth GR; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, 02115, USA.
Hurley JD; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, 02115, USA.
Wellner A; Department of Chemistry, University of California, Irvine, CA, 92697, USA.
Shaw AY; Department of Molecular Biology & Biochemistry, University of California, Irvine, CA, 92697, USA.
Miranda VG; Department of Biomedical Engineering, University of California, Irvine, CA, 92692, USA.
Min JK; Department of Systems Biology, Harvard Medical School, Boston, MA, 02115, USA.
Liu CC; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, 02115, USA.
Marks DS; Department of Systems Biology, Harvard Medical School, Boston, MA, 02115, USA.
Kruse AC; Department of Chemistry, University of California, Irvine, CA, 92697, USA.

Nat Commun ; 13(1): 7554, 2022 12 07.

Article em En | MEDLINE | ID: mdl-36477674

Assuntos

Fragmentos de Imunoglobulinas

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos de Imunoglobulinas Tipo de estudo: Prognostic_studies Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido

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