Metabolomics analysis of urine from patients with alcohol-associated liver disease reveals dysregulated caffeine metabolism.

Xu, Raobo; He, Liqing; Vatsalya, Vatsalya; Ma, Xipeng; Kim, Seongho; Mueller, Eugene G; Feng, Wenke; McClain, Craig J; Zhang, Xiang

Xu, Raobo; He, Liqing; Vatsalya, Vatsalya; Ma, Xipeng; Kim, Seongho; Mueller, Eugene G; Feng, Wenke; McClain, Craig J; Zhang, Xiang.

Afiliação

Xu R; Department of Chemistry, University of Louisville, Louisville, Kentucky.
He L; Alcohol Research Center, University of Louisville School of Medicine, Louisville, Kentucky.
Vatsalya V; Hepatobiology and Toxicology Center of Biomedical Research Excellence, University of Louisville School of Medicine Louisville, Louisville, Kentucky.
Ma X; Center for Regulatory and Environmental Analytical Metabolomics, University of Louisville, Louisville, Kentucky.
Kim S; Department of Chemistry, University of Louisville, Louisville, Kentucky.
Mueller EG; Alcohol Research Center, University of Louisville School of Medicine, Louisville, Kentucky.
Feng W; Hepatobiology and Toxicology Center of Biomedical Research Excellence, University of Louisville School of Medicine Louisville, Louisville, Kentucky.
McClain CJ; Center for Regulatory and Environmental Analytical Metabolomics, University of Louisville, Louisville, Kentucky.
Zhang X; Alcohol Research Center, University of Louisville School of Medicine, Louisville, Kentucky.

Am J Physiol Gastrointest Liver Physiol ; 324(2): G142-G154, 2023 02 01.

Article em En | MEDLINE | ID: mdl-36513601

Assuntos

Doença Hepática Terminal; Hepatopatias Alcoólicas; Humanos; Cafeína/metabolismo; Índice de Gravidade de Doença; Hepatopatias Alcoólicas/urina; Metabolômica/métodos; Biomarcadores/urina

Palavras-chave

alcohol-associated liver disease; caffeine metabolism; metabolomics; urine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença Hepática Terminal / Hepatopatias Alcoólicas Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Am J Physiol Gastrointest Liver Physiol Assunto da revista: FISIOLOGIA / GASTROENTEROLOGIA Ano de publicação: 2023 Tipo de documento: Article País de publicação: Estados Unidos

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