CaExTun: Mitigating Cas9-Related Toxicity in <i>Streptomyces</i> through Species-Specific Expression Tuning with Randomized Constitutive Promoters.

Je, Hyun-Woo; Ji, Chang-Hun; Kim, Jun-Yong; Kang, Hahk-Soo

CaExTun: Mitigating Cas9-Related Toxicity in Streptomyces through Species-Specific Expression Tuning with Randomized Constitutive Promoters.

Je, Hyun-Woo; Ji, Chang-Hun; Kim, Jun-Yong; Kang, Hahk-Soo.

Afiliação

Je HW; Department of Biomedical Science and Engineering, Konkuk University, Seoul 05029, Republic of Korea.
Ji CH; Department of Biomedical Science and Engineering, Konkuk University, Seoul 05029, Republic of Korea.
Kim JY; Department of Biomedical Science and Engineering, Konkuk University, Seoul 05029, Republic of Korea.
Kang HS; Department of Biomedical Science and Engineering, Konkuk University, Seoul 05029, Republic of Korea.

ACS Synth Biol ; 12(1): 61-70, 2023 01 20.

Article em En | MEDLINE | ID: mdl-36516042

Assuntos

Streptomyces; Streptomyces/genética; Streptomyces/metabolismo; Sistemas CRISPR-Cas/genética; Regiões Promotoras Genéticas/genética; Edição de Genes

Palavras-chave

CRISPR/Cas9; Cas9 toxicity; Streptomyces; constitutive promoter; genome engineering

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Streptomyces Tipo de estudo: Clinical_trials Idioma: En Revista: ACS Synth Biol Ano de publicação: 2023 Tipo de documento: Article País de publicação: Estados Unidos

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