Structural Basis for Inhibition of Mutant EGFR with Lazertinib (YH25448).

Heppner, David E; Wittlinger, Florian; Beyett, Tyler S; Shaurova, Tatiana; Urul, Daniel A; Buckley, Brian; Pham, Calvin D; Schaeffner, Ilse K; Yang, Bo; Ogboo, Blessing C; May, Earl W; Schaefer, Erik M; Eck, Michael J; Laufer, Stefan A; Hershberger, Pamela A

Heppner, David E; Wittlinger, Florian; Beyett, Tyler S; Shaurova, Tatiana; Urul, Daniel A; Buckley, Brian; Pham, Calvin D; Schaeffner, Ilse K; Yang, Bo; Ogboo, Blessing C; May, Earl W; Schaefer, Erik M; Eck, Michael J; Laufer, Stefan A; Hershberger, Pamela A.

Afiliação

Heppner DE; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, New York 14260, United States.
Wittlinger F; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York 14203, United States.
Beyett TS; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.
Shaurova T; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.
Urul DA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, United States.
Buckley B; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York 14203, United States.
Pham CD; AssayQuant Technologies, Inc., 260 Cedar Hill St., Marlboro, Massachusetts 01752, United States.
Schaeffner IK; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, New York 14203, United States.
Yang B; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, New York 14260, United States.
Ogboo BC; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.
May EW; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, United States.
Schaefer EM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.
Eck MJ; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, United States.
Laufer SA; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, New York 14260, United States.
Hershberger PA; AssayQuant Technologies, Inc., 260 Cedar Hill St., Marlboro, Massachusetts 01752, United States.

ACS Med Chem Lett ; 13(12): 1856-1863, 2022 Dec 08.

Article em En | MEDLINE | ID: mdl-36518696

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

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