Becker and limb-girdle muscular dystrophy associated with pituitary dwarfism.
J Neurol
; 234(6): 430-2, 1987 Aug.
Article
em En
| MEDLINE
| ID: mdl-3655848
ABSTRACT
In 1981 a report appeared of a patient with Duchenne muscular dystrophy associated with dwarfism caused by growth hormone deficiency, in whom the muscular disease was unusually benign. The authors suggested that the benign course might be related to the growth hormone deficiency and dwarfism. Other authors later supported this idea, having observed that in dystrophic mice and hamsters with congenital and experimentally induced pituitary dwarfism, respectively, pathological expressions of the dystrophy were markedly reduced. In this paper one case of Becker and one of limb-girdle dystrophy, each associated with short stature and growth hormone deficiency are described. In these cases the disease did not have a particularly benign course. It is concluded that caution is necessary, at least in certain cases, before an association between reduced muscular growth and the dystrophic process can be assumed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Nanismo Hipofisário
/
Distrofias Musculares
Tipo de estudo:
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Neurol
Ano de publicação:
1987
Tipo de documento:
Article
País de afiliação:
Itália