A Randomized Control Trial of 20% Glycolic Acid Versus 30% Salicylic Acid in the Management of Molluscum Contagiosum.
J Cutan Aesthet Surg
; 15(3): 249-253, 2022.
Article
em En
| MEDLINE
| ID: mdl-36561412
ABSTRACT
Background:
Molluscum contagiosum (MC) is a common self-limiting viral infection of the skin. Many therapeutic agents have been used for it with varying success rates.Objective:
To evaluate and compare the efficacy and safety profile of topical 20% glycolic acid and 30% salicylic acid in the treatment of MC in pediatric patients. Materials andMethods:
All patients of MC between 1 and 15 years of age attending the outpatient department of dermatology were randomized into two treatment groups A and B. Group A was treated with 20% glycolic acid solution, and group B was treated with 30% salicylic acid solution daily for 4 weeks. Parents of patients were instructed to apply the medication once daily at night for 1 h on the lesions only. The assessment of response and side effects were analyzed in all the patients weekly for 4 weeks during the daily treatment protocol. Follow-up was done monthly for 3 months after the completion of therapy.Results:
At the end of 4 weeks, group A patients (60 patients) were treated with 20% glycolic acid out of which 34 (56.66%) patients had a complete clearance of lesions. Group B patients were treated with 30% salicylic acid out of which 38 (63.33%) had a complete clearance of lesions. Secondary bacterial infection was the most common side effect followed by postinflammatory hyperpigmentation in both groups.Conclusion:
30% salicylic acid was found to be more effective and has less side-effect profile in the treatment of MC than 20% glycolic acid.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Clinical_trials
/
Guideline
Idioma:
En
Revista:
J Cutan Aesthet Surg
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Índia