Improved synthesis of deoxyalpinoid B and quantification of antileishmanial activity of deoxyalpinoid B and sulforaphane.

Leary, Emma; Anderson, Ethan T; Keyes, Jasmine K; Huskie, Tristan R; Blake, David J; Miller, Kenneth A

Leary, Emma; Anderson, Ethan T; Keyes, Jasmine K; Huskie, Tristan R; Blake, David J; Miller, Kenneth A.

Afiliação

Leary E; Department of Biology, Fort Lewis College, 1000 Rim Drive, Durango, CO 81301, United States.
Anderson ET; Department of Biology, Fort Lewis College, 1000 Rim Drive, Durango, CO 81301, United States.
Keyes JK; Department of Chemistry and Biochemistry, Fort Lewis College, 1000 Rim Drive, Durango, CO 81301, United States.
Huskie TR; Department of Chemistry and Biochemistry, Fort Lewis College, 1000 Rim Drive, Durango, CO 81301, United States.
Blake DJ; Department of Biology, Fort Lewis College, 1000 Rim Drive, Durango, CO 81301, United States.
Miller KA; Department of Chemistry and Biochemistry, Fort Lewis College, 1000 Rim Drive, Durango, CO 81301, United States. Electronic address: miller_k@fortlewis.edu.

Bioorg Med Chem ; 78: 117136, 2023 01 15.

Article em En | MEDLINE | ID: mdl-36565668

Assuntos

Antiprotozoários; Leishmania donovani; Isotiocianatos/farmacologia; Sulfóxidos/farmacologia

Palavras-chave

Deoxyalpinoid B; Leishmania donovani; Leishmania infantatum; Leishmaniasis; Meyer-Schuster rearrangement; Sulforaphane

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leishmania donovani / Antiprotozoários Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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