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Development of novel S-N3-DABO derivatives as potent non-nucleoside reverse transcriptase inhibitors with improved potency and selectivity.
Ling, Xu; Hao, Qing-Qing; Huang, Wen-Juan; Pannecouque, Christophe; De Clercq, Erik; Wang, Shuai; Chen, Fen-Er.
Afiliação
  • Ling X; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, Shanghai, 200433, PR China; Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai, 200433, PR China; Sichuan Research Center for Drug Precision Industria
  • Hao QQ; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, Shanghai, 200433, PR China; Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai, 200433, PR China; Sichuan Research Center for Drug Precision Industria
  • Huang WJ; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, Shanghai, 200433, PR China; Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai, 200433, PR China.
  • Pannecouque C; Rega Institute for Medical Research, KU Leuven, Herestraat 49, B-3000, Leuven, Belgium.
  • De Clercq E; Rega Institute for Medical Research, KU Leuven, Herestraat 49, B-3000, Leuven, Belgium.
  • Wang S; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, Shanghai, 200433, PR China; Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai, 200433, PR China. Electronic address: shuaiwang@fudan.edu.cn.
  • Chen FE; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, Shanghai, 200433, PR China; Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai, 200433, PR China; Sichuan Research Center for Drug Precision Industria
Eur J Med Chem ; 247: 115042, 2023 Feb 05.
Article em En | MEDLINE | ID: mdl-36577220

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: HIV-1 / Fármacos Anti-HIV Idioma: En Revista: Eur J Med Chem Ano de publicação: 2023 Tipo de documento: Article País de publicação: França

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: HIV-1 / Fármacos Anti-HIV Idioma: En Revista: Eur J Med Chem Ano de publicação: 2023 Tipo de documento: Article País de publicação: França